Yuru Liang

Potent Antitumor Activities and Structure Basis of the Chiral β-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin

Pengfei Zhou, Yan Liu, Lu Zhou et al. · Journal of Medicinal Chemistry · 2016 · 86 citations

Compound 9, Chemical Biology, Combretastatin A-4 Binding +18

Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β -lactam bridged combretastatin A-4 analogues as potent antitumor agents

Pengfei Zhou, Yuru Liang, Hao Zhang et al. · European Journal of Medicinal Chemistry · 2017 · 66 citations

Medicinal Chemistry, Cocrystal Structures, Drug Discovery +8

Design, synthesis, antitumor activities and biological studies of novel diaryl substituted fused heterocycles as dual ligands targeting tubulin and katanin

Feng Gao, Yuru Liang, Pengfei Zhou et al. · European Journal of Medicinal Chemistry · 2019 · 42 citations · Full text

Medicinal Chemistry, Dual Ligands, Biochemistry +8

Design, synthesis, and biological evaluation of hydantoin bridged analogues of combretastatin A-4 as potential anticancer agents

Mao Zhang, Yuru Liang, Huan Li et al. · Bioorganic & Medicinal Chemistry · 2017 · 36 citations

Medicinal Chemistry, Polymer-drug Conjugate, Medicine +8

Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis

Mingming Liu, Yuru Liang, Zhongzhen Zhu et al. · Journal of Medicinal Chemistry · 2019 · 34 citations · Full text