Peter J. Neame

The structure of aggrecan fragments in human synovial fluid. evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis

Stefan Lohmander, Peter J. Neame, John D. Sandy · Arthritis & Rheumatism · 1993 · 437 citations

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain.

John D. Sandy, Carl R. Flannery, Peter J. Neame et al. · Journal of Clinical Investigation · 1992 · 414 citations · Full text

Aggrecan Fragments, Orthopaedic Surgery, Inflammatory Arthritis +18

Degradation of cartilage aggrecan by collagenase‐3 (MMP‐13)

Amanda Fosang, Karena Last, Vera Knäuper et al. · FEBS Letters · 1996 · 376 citations · Full text

Mmp Family, Immunology, Pathology +17

The interglobular domain of cartilage aggrecan is cleaved by PUMP, gelatinases, and cathepsin B.

Amanda Fosang, Peter J. Neame, Karena Last et al. · Journal of Biological Chemistry · 1992 · 297 citations · Full text

Amino Acids, Pathology, Chemical Biology +21

Catabolism of aggrecan in cartilage explants. Identification of a major cleavage site within the interglobular domain

John D. Sandy, Peter J. Neame, Raymond Boynton et al. · Journal of Biological Chemistry · 1991 · 287 citations · Full text

Glycobiology, Bone Repair, Pathology +16