Carl R. Flannery

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

S.S. Glasson, Roger Askew, Barbara Sheppard et al. · Nature · 2005 · 1.3K citations

Dentistry, Genetics, Molecular Genetics +14

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain.

John D. Sandy, Carl R. Flannery, Peter J. Neame et al. · Journal of Clinical Investigation · 1992 · 416 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Articular Cartilage Superficial Zone Protein (SZP) Is Homologous to Megakaryocyte Stimulating Factor Precursor and Is a Multifunctional Proteoglycan with Potential Growth-Promoting, Cytoprotective, and Lubricating Properties in Cartilage Metabolism

Carl R. Flannery, Clare Hughes, Barbara L. Schumacher et al. · Biochemical and Biophysical Research Communications · 1999 · 357 citations

Medicine, Cell Biology, Molecular Biology +17

Catabolism of aggrecan in cartilage explants. Identification of a major cleavage site within the interglobular domain

John D. Sandy, Peter J. Neame, Raymond Boynton et al. · Journal of Biological Chemistry · 1991 · 287 citations · Full text

Life Sciences, Molecular Biology, Cartilage Repair +12

Characterization of and osteoarthritis susceptibility in ADAMTS‐4–knockout mice

S.S. Glasson, Roger Askew, Barbara Sheppard et al. · Arthritis & Rheumatism · 2004 · 281 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +12