Concepedia
Statistics
Publications
8
Citations
277
H-Index
Active since
2009
Affiliations
Masaryk University(Current)
Central European Institute of Technology – Masaryk University
Central European Institute of Technology
University Hospital Brno
St. Anne's University Hospital Brno
Jiří Sedmík is an author at Masaryk University specializing in life sciences, medicine, and brain organoid development.
Publications per year
2009–2023
Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development
Tereza Váňová, Jiří Sedmík, Jan Raška et al. · Cell Reports · 2023 · 76 citations · Full text
Life Sciences, Developmental Biology, Neuroscience +17
Bi-allelic ADARB1 Variants Associated with Microcephaly, Intellectual Disability, and Seizures
Tiong Yang Tan, Jiří Sedmík, Mark P. Fitzgerald et al. · The American Journal of Human Genetics · 2020 · 50 citations · Full text
Life Sciences, Genetics, Neuroscience +14
Activation of innate immunity by mitochondrial dsRNA in mouse cells lacking p53 protein
Dagmara Marta Wiatrek, Maria Elena Candela, Jiří Sedmík et al. · RNA · 2019 · 30 citations · Full text
Life Sciences, Immunology, Molecular Biology +17
Biallelic variants in <i>ADARB1</i>, encoding a dsRNA-specific adenosine deaminase, cause a severe developmental and epileptic encephalopathy
Reza Maroofian, Jiří Sedmík, Neda Mazaheri et al. · Journal of Medical Genetics · 2020 · 30 citations · Full text
Medicine, Genetics, Molecular Genetics +17
Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate
Michal Nemergut, Sérgio M. Marques, Lukáš Uhrík et al. · Molecular Neurodegeneration · 2023 · 25 citations · Full text
Life Sciences, Biochemistry, Molecular Biology +17
1–5 of 8