Vivien R. Sutton

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

Astrid A. Ruefli, Michael J. Ausserlechner, David Bernhard et al. · Proceedings of the National Academy of Sciences · 2001 · 489 citations · Full text

Histone Deacetylase Inhibitor, Apoptosis, Cell Death +16

Tumor immune evasion arises through loss of TNF sensitivity

Conor J. Kearney, Stephin J. Vervoort, Simon J. Hogg et al. · Science Immunology · 2018 · 384 citations

Initiation of Apoptosis by Granzyme B Requires Direct Cleavage of Bid, but Not Direct Granzyme B–Mediated Caspase Activation

Vivien R. Sutton, Joanne E. Davis, Michael Cancilla et al. · The Journal of Experimental Medicine · 2000 · 366 citations · Full text

The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis

Mark J. Smyth, Erika Krasovskis, Vivien R. Sutton et al. · Proceedings of the National Academy of Sciences · 1998 · 359 citations

Tumor Biology, Drug-resistant Tumor Cells, Oncology +15

A Cytosolic Granzyme B Inhibitor Related to the Viral Apoptotic Regulator Cytokine Response Modifier A Is Present in Cytotoxic Lymphocytes

Jiuru Sun, Catherina H. Bird, Vivien R. Sutton et al. · Journal of Biological Chemistry · 1996 · 297 citations · Full text