Matthew A. Cerny

Synthetic Inhibitors of Cytochrome P-450 2A6:  Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization

Jason K. Yano, Travis T. Denton, Matthew A. Cerny et al. · Journal of Medicinal Chemistry · 2006 · 127 citations · Full text

Cytochrome P450-Catalyzed Oxidation of <i>N</i>-Benzyl-<i>N</i>-cyclopropylamine Generates Both Cyclopropanone Hydrate and 3-Hydroxypropionaldehyde via Hydrogen Abstraction, Not Single Electron Transfer

Matthew A. Cerny, Robert P. Hanzlik · Journal of the American Chemical Society · 2006 · 60 citations

Suicide Substrate Activity, Set Oxidation, Engineering +19

Identification of Glycochenodeoxycholate 3‐O‐Glucuronide and Glycodeoxycholate 3‐O‐Glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers

Mikko Neuvonen, Päivi Hirvensalo, Aleksi Tornio et al. · Clinical Pharmacology & Therapeutics · 2020 · 44 citations · Full text

G Protein–Coupled Bile Acid Receptor 1 Stimulation Mediates Arterial Vasodilation through a KCa1.1 (BKCa)–Dependent Mechanism

Ryan M. Fryer, Khing Jow Ng, Suzanne G. Nodop Mazurek et al. · Journal of Pharmacology and Experimental Therapeutics · 2014 · 43 citations

Effective Application of Metabolite Profiling in Drug Design and Discovery

Matthew A. Cerny, Amit S. Kalgutkar, R. Scott Obach et al. · Journal of Medicinal Chemistry · 2020 · 43 citations · Full text

Bioorganic Chemistry, Metabolomic Profiling, Drug Metabolites +20