Concepedia

Author

Aleksi Tornio

University of HelsinkiORCID

Also Known As

A Tornio, A. Tornio, Aleksi Tornio

94

Publications

2.7K

Citations

29

H-Index

25

Concepts

All Affiliations

University of HelsinkiHelsinki University HospitalUniversity of TurkuTurku University Hospital
AT

About

Aleksi Tornio is an author at University of Helsinki specializing in pharmacology, pharmacotherapy, and medicine.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

7

7

394

2

Biochemistry

4

4

301

3

Health Sciences

1

1

29

4

Natural Sciences

1

1

42

5

Biostatistics

1

1

35

Aleksi Tornio

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43

Publications

2K

Citations

27

H-Index

YearCitations

SLCO1B1 polymorphism markedly affects the pharmacokinetics of lovastatin acid

Aleksi Tornio, Juha Vakkilainen, Mikko Neuvonen,

Pharmacogenetics and Genomics

2015

406

Glucuronidation Converts Clopidogrel to a Strong Time-Dependent Inhibitor of CYP2C8: A Phase II Metabolite as a Perpetrator of Drug–Drug Interactions

Aleksi Tornio, Anne M. Filppula, O Kailari,

Clinical Pharmacology & Therapeutics

2014

139

Trimethoprim and the CYP2C8*3 Allele Have Opposite Effects on the Pharmacokinetics of Pioglitazone

Aleksi Tornio, Mikko Niemi, Pertti J. Neuvonen,

Drug Metabolism and Disposition

2007

112

The Effect of Gemfibrozil on Repaglinide Pharmacokinetics Persists for at Least 12 h After the Dose: Evidence for Mechanism-based Inhibition of CYP2C8 In Vivo

Aleksi Tornio, Mikko Niemi, Mikko Neuvonen,

Clinical Pharmacology & Therapeutics

2008

89

Itraconazole, gemfibrozil and their combination markedly raise the plasma concentrations of loperamide

Mikko Niemi, Aleksi Tornio, Marja K. Pasanen,

European Journal of Clinical Pharmacology

2006

85

Carboxylesterase 1 c.428G>A single nucleotide variation increases the antiplatelet effects of clopidogrel by reducing its hydrolysis in humans

E. Katriina Tarkiainen, MT Holmberg, Aleksi Tornio,

Clinical Pharmacology & Therapeutics

2015

76

Clopidogrel Increases Dasabuvir Exposure With or Without Ritonavir, and Ritonavir Inhibits the Bioactivation of Clopidogrel

Matti K. Itkonen, Aleksi Tornio, Outi Lapatto‐Reiniluoto,

Clinical Pharmacology & Therapeutics

2018

65

Grapefruit Juice Inhibits the Metabolic Activation of Clopidogrel

Mikko T. Holmberg, Aleksi Tornio, Mikko Neuvonen,

Clinical Pharmacology & Therapeutics

2013

63

CYP2C8 Activity Recovers within 96 Hours after Gemfibrozil Dosing: Estimation of CYP2C8 Half-Life Using Repaglinide as an in Vivo Probe

Janne T. Backman, Johanna Honkalammi, Mikko Neuvonen,

Drug Metabolism and Disposition

2009

56

A common missense variant of LILRB5 is associated with statin intolerance and myalgia

Moneeza K. Siddiqui, Cyrielle Maroteau, Abirami Veluchamy,

European Heart Journal

2017

49

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