Isabel Zaror

Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer

Matthew T. Burger, Sabina Pecchi, Allan S. Wagman et al. · ACS Medicinal Chemistry Letters · 2011 · 248 citations · Full text

2,4-Bismorpholino 6-Heterocyclic Pyrimidines, Pi3 Kinase Inhibitor, Orally Bioavailable Class +18

Rationally Designed PI3Kα Mutants to Mimic ATR and Their Use to Understand Binding Specificity of ATR Inhibitors

Yipin Lu, Mark Knapp, Kenneth Crawford et al. · Journal of Molecular Biology · 2017 · 40 citations · Full text

Molecular Pharmacology, Pikk Family, Protein Function +15

Baculovirus-driven protein expression in insect cells: A benchmarking study

Peggy Stolt-Bergner, Christian Benda, Tim Bergbrede et al. · Journal of Structural Biology · 2018 · 34 citations

Molecular Virology, Insect Virus, Insect Cells +5

Abstract 4498: Biological characterization of NVP-BKM120, a novel inhibitor of phosphoinosotide 3-kinase in Phase I/II clinical trials

Charles F. Voliva, Sabina Pecchi, Matthew T. Burger et al. · Cancer Research · 2010 · 32 citations

Novel Inhibitor, Pi3k Inhibitors, Additional Pi3k Inhibitors +25

Inhibition of prenylated KRAS in a lipid environment

Johanna M. Jansen, Charles Wartchow, Wolfgang Jahnke et al. · PLoS ONE · 2017 · 31 citations · Full text

Signal Transduction, Biochemistry, Kras Inhibition +13