Johanna M. Jansen

D3R grand challenge 4: blind prediction of protein–ligand poses, affinity rankings, and relative binding free energies

conor parks, Zied Gaieb, Michael Chiu et al. · Journal of Computer-Aided Molecular Design · 2020 · 138 citations · Full text

Blind Prediction, Engineering, Protein–ligand Poses +12

Design, Structure−Activity Relationships and in Vivo Characterization of 4-Amino-3-benzimidazol-2-ylhydroquinolin-2-ones: A Novel Class of Receptor Tyrosine Kinase Inhibitors

Paul A. Renhowe, Sabina Pecchi, Cynthia M. Shafer et al. · Journal of Medicinal Chemistry · 2008 · 134 citations · Full text

Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site

Zhenhao Fang, Christopher B. Marshall, Tadateru Nishikawa et al. · Cell chemical biology · 2018 · 90 citations · Full text

Signal Transduction, Signaling Pathway, Biochemistry +11

A Unified and Quantitative Receptor Model for the Microtubule Binding of Paclitaxel and Epothilone

Minmin Wang, Xiaoyang Xia, Yohan Kim et al. · Organic Letters · 1999 · 88 citations

Drug Target, Cytoskeleton, Peptide Science +23

Design and Synthesis of Orally Bioavailable Benzimidazoles as Raf Kinase Inhibitors

Savithri Ramurthy, Sharadha Subramanian, Mina Aikawa et al. · Journal of Medicinal Chemistry · 2008 · 76 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Pharmaceutical Science +13