Johanna M. Jansen

D3R grand challenge 4: blind prediction of protein–ligand poses, affinity rankings, and relative binding free energies

conor parks, Zied Gaieb, Michael Chiu et al. · Journal of Computer-Aided Molecular Design · 2020 · 145 citations · Full text

Life Sciences, Bioinformatics, Medicinal Chemistry +17

Design, Structure−Activity Relationships and in Vivo Characterization of 4-Amino-3-benzimidazol-2-ylhydroquinolin-2-ones: A Novel Class of Receptor Tyrosine Kinase Inhibitors

Paul A. Renhowe, Sabina Pecchi, Cynthia M. Shafer et al. · Journal of Medicinal Chemistry · 2008 · 135 citations · Full text

Medicine, Oncology, Pharmacology +13

Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site

Zhenhao Fang, Christopher B. Marshall, Tadateru Nishikawa et al. · Cell chemical biology · 2018 · 91 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

A Unified and Quantitative Receptor Model for the Microtubule Binding of Paclitaxel and Epothilone

Minmin Wang, Xiaoyang Xia, Yohan Kim et al. · Organic Letters · 1999 · 88 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Profile-QSAR: A Novel <i>meta</i>-QSAR Method that Combines Activities across the Kinase Family To Accurately Predict Affinity, Selectivity, and Cellular Activity

Éric Martin, Prasenjit Mukherjee, David C. Sullivan et al. · Journal of Chemical Information and Modeling · 2011 · 76 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16