Concepedia

Author

A. Pieter J. van den Heuvel

Penn State Milton S. Hershey Medical Center

Also Known As

A P J van den Heuvel, A. Heuvel, A. Pieter J. Van Den Heuvel, A. Pieter J. Van den Heuvel, A. Pieter J. van den Heuvel, A. Pieter J. van den HEUVEL

37

Publications

1.8K

Citations

13

H-Index

27

Concepts

All Affiliations

Penn State Milton S. Hershey Medical CenterOncoceutics (United States)Fox Chase Cancer CenterHarvard UniversityNational Cancer Institute
AP

About

A. Pieter J. van den Heuvel is an author at Penn State Milton S. Hershey Medical Center specializing in tumor biology, medicine, and tumor microenvironment.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

4

4

340

2

Cell Biology

3

3

286

3

Immunology

2

2

85

4

Health Sciences

1

1

44

5

Biochemistry

1

1

211

A. Pieter J. van den Heuvel

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11

Publications

1K

Citations

11

H-Index

YearCitations

Analysis of glutamine dependency in non-small cell lung cancer

A. Pieter J. van den Heuvel, Junping Jing, Richard Wooster,

Cancer Biology & Therapy

2012

211

ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases

C. Leah B. Kline, A. Pieter J. van den Heuvel, Joshua E. Allen,

Science Signaling

2016

195

Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth

Troy E. Messick, Garry R. Smith, Samantha S. Soldan,

Science Translational Medicine

2019

117

Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53

Shengliang Zhang, Lanlan Zhou, Bo Hong,

Cancer Research

2015

106

Prodigiosin Rescues Deficient p53 Signaling and Antitumor Effects via Upregulating p73 and Disrupting Its Interaction with Mutant p53

Bo Hong, Varun V. Prabhu, Shengliang Zhang,

Cancer Research

2013

87

Binding of protein kinase B to the plakin family member periplakin

A. Pieter J. van den Heuvel, Alida M.M. de Vries-Smits, Pascale C. van Weeren,

Journal of Cell Science

2002

83

Direct control of caveolin-1 expression by FOXO transcription factors

A. Pieter J. van den Heuvel, Almut Schulze, Boudewijn Burgering

Biochemical Journal

2005

59

Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies

Varun V. Prabhu, Mala K. Talekar, Amriti R. Lulla,

Cell Cycle

2017

54

Genetic and Pharmacological Screens Converge in Identifying FLIP, BCL2, and IAP Proteins as Key Regulators of Sensitivity to the TRAIL-Inducing Anticancer Agent ONC201/TIC10

Joshua E. Allen, Varun V. Prabhu, Mala K. Talekar,

Cancer Research

2015

45

Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors

Varun V. Prabhu, Amriti R. Lulla, Neel S. Madhukar,

PLoS ONE

2017

44

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