A. Rosowsky

2,4-Diaminothieno[2,3-d]pyrimidines as antifolates and antimalarials. 2. Synthesis of 2,4-diaminopyrido[4',3':4,5]thieno[2,3-d]pyrimidines and 2,4-diamino-8H-thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidines

Michael Chaykovsky, Mingxiang Lin, A. Rosowsky et al. · Journal of Medicinal Chemistry · 1973 · 64 citations

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +13

Structure‐based approach to pharmacophore identification, <i>in silico</i> screening, and three‐dimensional quantitative structure–activity relationship studies for inhibitors of <i>Trypanosoma cruzi</i> dihydrofolate reductase function

Norbert Schormann, Olga Senkovich, Kiera Walker et al. · Proteins Structure Function and Bioinformatics · 2008 · 41 citations

Dhfr Activity, Drug Target, Dhfr Domain +17

Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.

Myung S. Rhee, John Galivan, J E Wright et al. · Molecular Pharmacology · 1994 · 27 citations

Side chain modified 5-deazatolate and 5-deazatetrahydrotolate analogs as mammalian folylpolyglutamate synthetase and glycinamide ribonucleotide formyltransferase inhibitors: synthesis and in vitro biological evaluation. 47. N-[4-[[(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-6-yl)methyl]amino]benzoyl-L-glutamic acid, a novel a-ring analog of 2-desamino-5,8-dideazafolic acid

A. Rosowsky, Ronald A. Forsch, R G Moran · Journal of Medicinal Chemistry · 1992 · 19 citations · Full text

1,2-Dithiol-3-thione and dithioester analogues: potential radioprotectors

BA Teicher, J Stemwedel, TS Herman et al. · British Journal of Cancer · 1990 · 15 citations · Full text

Dithioester Analogues, Derivative (Chemistry), Organic Chemistry +3