Fenju Wei

Identification of Dihydrofuro[3,4-<i>d</i>]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties

Dongwei Kang, Heng Zhang, Zhao Wang et al. · Journal of Medicinal Chemistry · 2019 · 86 citations · Full text

Structure-Based Bioisosterism Yields HIV-1 NNRTIs with Improved Drug-Resistance Profiles and Favorable Pharmacokinetic Properties

Dongwei Kang, Da Feng, Yanying Sun et al. · Journal of Medicinal Chemistry · 2020 · 72 citations · Full text

Exploring the hydrophobic channel of NNIBP leads to the discovery of novel piperidine-substituted thiophene[3,2-d]pyrimidine derivatives as potent HIV-1 NNRTIs

Dongwei Kang, Da Feng, Tiziana Ginex et al. · Acta Pharmaceutica Sinica B · 2019 · 50 citations · Full text

Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel

Dongwei Kang, Francesc X. Ruiz, Da Feng et al. · Journal of Medicinal Chemistry · 2020 · 46 citations · Full text

Discovery of piperidine-substituted thiazolo[5,4-d]pyrimidine derivatives as potent and orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitors

Dongwei Kang, Tong Zhao, Zhao Wang et al. · Communications Chemistry · 2019 · 32 citations · Full text