Kenneth J. DiRico

Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor

Antonia F. Stepan, Chakrapani Subramanyam, Ivan Efremov et al. · Journal of Medicinal Chemistry · 2012 · 412 citations · Full text

Metabolism-Directed Design of Oxetane-Containing Arylsulfonamide Derivatives as γ-Secretase Inhibitors

Antonia F. Stepan, Kapil Karki, W. Scott McDonald et al. · Journal of Medicinal Chemistry · 2011 · 106 citations · Full text

Chemical Biology, Experimental Pharmacology, Pharmaceutical Chemistry +16

Concerted vs Stepwise Mechanisms in Dehydro-Diels–Alder Reactions

Aida Ajaz, Alexander Z. Bradley, Richard C. Burrell et al. · The Journal of Organic Chemistry · 2011 · 101 citations

Engineering, Heterocyclic, Alkene Metathesis +15

Acoustic Ejection Mass Spectrometry for High-Throughput Analysis

Hui Zhang, Chang Liu, Wenyi Hua et al. · Analytical Chemistry · 2021 · 96 citations · Full text

Engineering, Analytical Microsystems, Spectrochemical Analysis +19

Ultra-High-Throughput Acoustic Droplet Ejection-Open Port Interface-Mass Spectrometry for Parallel Medicinal Chemistry

Kenneth J. DiRico, Wenyi Hua, Chang Liu et al. · ACS Medicinal Chemistry Letters · 2020 · 84 citations · Full text

Engineering, Parallel Medicinal Chemistry, Hit Identification +21