Tatyana Adayev

Trisomy-driven overexpression of DYRK1A kinase in the brain of subjects with Down syndrome

W. K. Dowjat, Tatyana Adayev, Izabela Kuchna et al. · Neuroscience Letters · 2006 · 184 citations

Down Syndrome, Genetic Disorder, Genetics +6

Harmine is an ATP-competitive inhibitor for dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A)

Tatyana Adayev, Jerzy Węgiel, Yu‐Wen Hwang · Archives of Biochemistry and Biophysics · 2010 · 120 citations · Full text

Signal Transduction, Signaling Pathway, Medicine +8

The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome

Jerzy Węgiel, Karol Dowjat, Wojciech Kaczmarski et al. · Acta Neuropathologica · 2008 · 108 citations · Full text

Link Between DYRK1A Overexpression and Several-Fold Enhancement of Neurofibrillary Degeneration With 3-Repeat Tau Protein in Down Syndrome

Jerzy Węgiel, Wojciech Kaczmarski, Madhabi Barua et al. · Journal of Neuropathology & Experimental Neurology · 2010 · 94 citations · Full text

Sporadic Alzheimer Disease, Genetics, Neurochemical Biomarkers +24

The G protein-coupled 5-HT1A receptor causes suppression of caspase-3 through MAPK and protein kinase Cα

Tatyana Adayev, Indrani Ray, Rachna Sondhi et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2003 · 80 citations

Signal Transduction, Molecular Physiology, Signaling Pathway +9