Alec N. Woosley

Structural impact on SARS-CoV-2 spike protein by D614G substitution

Jun Zhang, Yongfei Cai, Tianshu Xiao et al. · Science · 2021 · 460 citations · Full text

Virus Structure, Viral Replication, G614 Spike +12

TGFβ promotes breast cancer stem cell self-renewal through an ILEI/LIFR signaling axis

Alec N. Woosley, Annamarie C. Dalton, George S. Hussey et al. · Oncogene · 2019 · 85 citations · Full text

Developmental Biology, Tissue Development, Breast Cancer Stem +9

Cathepsin-B-mediated cleavage of Disabled-2 regulates TGF-β-induced autophagy

Yong Jiang, Alec N. Woosley, N Sivalingam et al. · Nature Cell Biology · 2016 · 57 citations · Full text

Cell Autophagy, Signal Transduction, Autophagy +4

S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity

Zongyang Lv, Kimberly A. Rickman, Lingmin Yuan et al. · Molecular Cell · 2017 · 55 citations · Full text

Protein Function, Molecular Biology, Heme Signaling +6

Cooperative adaptation to therapy (CAT) confers resistance in heterogeneous non-small cell lung cancer

Morgan Craig, Kamran Kaveh, Alec N. Woosley et al. · PLoS Computational Biology · 2019 · 35 citations · Full text

Cancer Biology, Tumor Biology, Drug Resistance +20