Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes

Utz Krug, Christoph Röllig, Anja Koschmieder, +18

The Lancet

Hematological MalignancyPrognostic EvaluationMedicineMixed-phenotype Acute LeukemiaPrognosis +10

Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia

Stefanie Göllner, Thomas Oellerich, Shuchi Agrawal‐Singh, +25

Nature Medicine

Histone ModificationsChromatinHematological MalignancyOncologyMedicine +9

BISMA - Fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequences

Christian Rohde, Yingying Zhang, Richard Reinhardt, +1

BMC Bioinformatics

AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia

Fengbiao Zhou, Yi Liu, Christian Rohde, +27

Nature Cell Biology

Cell RegulationMedicineRadiation OncologyCancer BiologyCell Biology +3

DNA Methylation Analysis of Chromosome 21 Gene Promoters at Single Base Pair and Single Allele Resolution

Yingying Zhang, Christian Rohde, Sascha Tierling, +8

PLoS Genetics

Chimeric DNA methyltransferases target DNA methylation to specific DNA sequences and repress expression of target genes

Fuyang Li, Monika Papworth, Michal Minczuk, +4

Nucleic Acids Research

Epigenetic ChangeGeneticsDna MethylationMolecular BiologyTarget Genes +18

Alarmins MRP8 and MRP14 Induce Stress Tolerance in Phagocytes under Sterile Inflammatory Conditions

Judith Austermann, Judith Friesenhagen, Selina Kathleen Fassl, +16

Cell Reports

Epigenetic dysregulation of K_Ca3.1 channels induces poor prognosis in lung cancer

Etmar Bulk, Anne‐Sophie Ay, Mehdi Hammadi, +15

International Journal of Cancer

Tumor BiologyMedicineDna MethylationEpigenomic ChangesIon Channels +11

Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1

Maike Janssen, Christina Schmidt, Peter‐Martin Bruch, +33

Blood

Site-specific methylation of 18S ribosomal RNA by SNORD42A is required for acute myeloid leukemia cell proliferation

Cornelius Pauli, Yi Liu, Christian Rohde, +11

Blood