Karen Howland

<i>In Vitro</i> and <i>In Vivo</i> Characterization of CB-183,315, a Novel Lipopeptide Antibiotic for Treatment of Clostridium difficile

Carmela Mascio, Lawrence I. Mortin, Karen Howland et al. · Antimicrobial Agents and Chemotherapy · 2012 · 77 citations · Full text

Microbial Pathogens, Spontaneous Resistance Incidence, Antimicrobial Chemotherapy +24

Structure–Activity Relationship Studies of a Series of Semisynthetic Lipopeptides Leading to the Discovery of Surotomycin, a Novel Cyclic Lipopeptide Being Developed for the Treatment of <i>Clostridium difficile</i>-Associated Diarrhea

Ning Yin, Jing Li, Yong He et al. · Journal of Medicinal Chemistry · 2015 · 35 citations

Antimicrobial Drug Discovery, Derivatives, Pharmaceutical Chemistry +15

Reduced pulmonary surfactant interaction of daptomycin analogs via tryptophan replacement with alternative amino acids

Yong He, Jing Li, Nin Yin et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 21 citations

Tryptophan Replacement, Daptomycin Analogs, Biochemistry +9

In vitro activity of ceftolozane/tazobactam in combination with other classes of antibacterial agents

Cédric Jacqueline, Karen Howland, Laurent Chesnel · Journal of Global Antimicrobial Resistance · 2017 · 18 citations

Antibacterial Agents, Antifungal Agent, Antibiotics +10