Manjuan Liu

Structure Enabled Design of BAZ2-ICR, A Chemical Probe Targeting the Bromodomains of BAZ2A and BAZ2B

Ludovic Drouin, Sally McGrath, Lewis R. Vidler et al. · Journal of Medicinal Chemistry · 2015 · 100 citations · Full text

Crystal Structure, Baz2 Bromodomains, Molecular Biology +21

Structure-Based Design of Orally Bioavailable 1<i>H</i>-Pyrrolo[3,2-<i>c</i>]pyridine Inhibitors of Mitotic Kinase Monopolar Spindle 1 (MPS1)

Sébastien Naud, Isaac M. Westwood, Amir Faisal et al. · Journal of Medicinal Chemistry · 2013 · 79 citations · Full text

Pharmaceutical Science, Molecular Biology, Mps1 Inhibition +20

Achieving <i>In Vivo</i> Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders

Benjamin R. Bellenie, Kwai-Ming J. Cheung, Ana Varela et al. · Journal of Medicinal Chemistry · 2020 · 72 citations · Full text

A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms

Alan M. Jones, Isaac M. Westwood, James Osborne et al. · Scientific Reports · 2016 · 28 citations · Full text

Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase

Katie Pollock, Manjuan Liu, Mariola Zaleska et al. · Scientific Reports · 2019 · 28 citations · Full text