Laura Wiehle

Non-core Subunits of the PRC2 Complex Are Collectively Required for Its Target-Site Specificity

Jonas W. Højfeldt, Lin Hedehus, Anne Laugesen et al. · Molecular Cell · 2019 · 157 citations · Full text

Chromatin, Target-site Specificity, Molecular Biology +6

DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries

Laura Wiehle, Graeme J. Thorn, Günter Raddatz et al. · Genome Research · 2019 · 104 citations · Full text

A novel bispecific EGFR/Met antibody blocks tumor-promoting phenotypic effects induced by resistance to EGFR inhibition and has potent antitumor activity

Raffaella Castoldi, Veronika Ecker, Laura Wiehle et al. · Oncogene · 2013 · 61 citations · Full text

Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation

Laura Wiehle, Günter Raddatz, Tanja Musch et al. · Molecular and Cellular Biology · 2015 · 59 citations · Full text

Invasive Dna Methylation, Epigenetic Change, Genetics +16

Reconstruction of rearranged T‐cell receptor loci by whole genome and transcriptome sequencing gives insights into the initial steps of T‐cell prolymphocytic leukemia

Paurnima Patil, Agata Cieślak, Umut H. Toprak et al. · Genes Chromosomes and Cancer · 2019 · 19 citations · Full text

Mixed-phenotype Acute Leukemia, Immunology, Pathology +19