Jonas W. Højfeldt

Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

Sebastian Bender, Yujie Tang, Anders M. Lindroth et al. · Cancer Cell · 2013 · 821 citations · Full text

Neuro-oncology, Radiation Oncology, Pediatric Brain Tumors +9

EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

Faizaan Mohammad, Simon Weissmann, Benjamin Leblanc et al. · Nature Medicine · 2017 · 516 citations

Potential Therapeutic Target, Neuro-oncology, Pediatric Brain Tumors +11

Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2

Jonas W. Højfeldt, Anne Laugesen, Berthe M. Willumsen et al. · Nature Structural & Molecular Biology · 2018 · 224 citations · Full text

Chromatin, Systems Biology, Engineering +9

A Yoctoliter-Scale DNA Reactor for Small-Molecule Evolution

Margit Haahr Hansen, Peter Blakskjær, L. Petersen et al. · Journal of the American Chemical Society · 2009 · 187 citations · Full text

Engineering, Peptide Engineering, Molecular Biology +19

The lncRNA MIR31HG regulates p16INK4A expression to modulate senescence

Marta Montes, Morten M. Nielsen, Giulia Maglieri et al. · Nature Communications · 2015 · 186 citations · Full text