Carol A. Menard

Rational Targeting of Active-Site Tyrosine Residues Using Sulfonyl Fluoride Probes

Erik C. Hett, Hua Xu, Kieran F. Geoghegan et al. · ACS Chemical Biology · 2015 · 191 citations

Molecular Pharmacology, Drug Target, Biochemistry +15

Pyridone Methylsulfone Hydroxamate LpxC Inhibitors for the Treatment of Serious Gram-Negative Infections

Justin I. Montgomery, Matthew F. Brown, Usa Reilly et al. · Journal of Medicinal Chemistry · 2012 · 97 citations · Full text

Pharmaceutical Science, Pharmacotherapy, New Series +19

Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections

Matthew F. Brown, Usa Reilly, J. A. Abramite et al. · Journal of Medicinal Chemistry · 2011 · 97 citations · Full text

Thrombospondin and fibronectin are synthesized by neutrophils in human inflammatory joint disease and in a rabbit model of in vivo neutrophil activation.

Christophe Kreis, Monique La Fleur, Carol A. Menard et al. · The Journal of Immunology · 1989 · 50 citations

Immunology, Vivo Neutrophil Activation, Rabbit Model +21

Heterocyclic methylsulfone hydroxamic acid LpxC inhibitors as Gram-negative antibacterial agents

Laura A. McAllister, Justin I. Montgomery, J. A. Abramite et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 37 citations · Full text

Antibacterial Agents, Medicinal Chemistry, Antimicrobial Drug Discovery +15