Douglas Strathdee

CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma

Colin W. Steele, Saadia A. Karim, Joshua D.G. Leach et al. · Cancer Cell · 2016 · 819 citations · Full text

SynGAP Regulates ERK/MAPK Signaling, Synaptic Plasticity, and Learning in the Complex with Postsynaptic Density 95 and NMDA Receptor

Noboru H. Komiyama, Ayako M. Watabe, Holly J. Carlisle et al. · Journal of Neuroscience · 2002 · 385 citations · Full text

Synaptic Transmission, Neurotransmitter, Neurotransmission +18

Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis

Simone Cardaci, Liang Zheng, Gillian Mackay et al. · Nature Cell Biology · 2015 · 277 citations · Full text

Biosynthesis, Energy Metabolism, Biochemistry +11

CRISPR/Cas9-Mediated <i>Trp53</i> and <i>Brca2</i> Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma

Josephine Walton, Julianna Blagih, Darren Ennis et al. · Cancer Research · 2016 · 237 citations · Full text

Association of Mouse <i>Dlg4</i> (PSD-95) Gene Deletion and Human <i>DLG4</i> Gene Variation With Phenotypes Relevant to Autism Spectrum Disorders and Williams' Syndrome

Michael Feyder, Rose‐Marie Karlsson, Poonam Mathur et al. · American Journal of Psychiatry · 2010 · 222 citations · Full text