Josephine Walton

CRISPR/Cas9-Mediated <i>Trp53</i> and <i>Brca2</i> Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma

Josephine Walton, Julianna Blagih, Darren Ennis et al. · Cancer Research · 2016 · 246 citations · Full text

Medicine, Genetics, Oncology +17

Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses

Julianna Blagih, Fabio Zani, Probir Chakravarty et al. · Cell Reports · 2020 · 179 citations · Full text

Medicine, Cancer Biology, Oncology +17

Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING

Marine Bruand, David Barras, Marco Mina et al. · Cell Reports · 2021 · 138 citations · Full text

Medicine, Immunology, Oncology +17

CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity

Josephine Walton, Malcolm Farquharson, Susan Mason et al. · Scientific Reports · 2017 · 122 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Longitudinal immune characterization of syngeneic tumor models to enable model selection for immune oncology drug discovery

Molly A. Taylor, Adina Hughes, Josephine Walton et al. · Journal for ImmunoTherapy of Cancer · 2019 · 102 citations · Full text

Life Sciences, Immunology, Oncology +17