Colin W. Steele

CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma

Colin W. Steele, Saadia A. Karim, Joshua D.G. Leach et al. · Cancer Cell · 2016 · 838 citations · Full text

Medicine, Cancer Biology, Oncology +17

Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis

René Jackstadt, Sander R. van Hooff, Joshua D.G. Leach et al. · Cancer Cell · 2019 · 449 citations · Full text

Medicine, Cancer Biology, Oncology +17

Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis

Thomas Jamieson, Mairi Clarke, Colin W. Steele et al. · Journal of Clinical Investigation · 2012 · 383 citations

Life Sciences, Immunology, Oncology +17

Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy

Bryan W. Miller, Jennifer P. Morton, Mark Pinese et al. · EMBO Molecular Medicine · 2015 · 266 citations · Full text

Medicine, Oncology, Pharmacology +17

The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy

Claire S. Reader, Sabari Vallath, Colin W. Steele et al. · The Journal of Pathology · 2019 · 111 citations · Full text

Medicine, Cancer Biology, Oncology +16