Digant Nayak

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Active since

2009

Affiliations

The University of Texas at San Antonio Health Science Center(Current)

National University of Singapore

Wrocław University of Science and Technology

AGH University of Krakow

MUSC Hollings Cancer Center

Digant Nayak is an author at The University of Texas at San Antonio Health Science Center specializing in life sciences, structural biology, and molecular biology.

ORCID

Publications per year

2009–2024

Publications

Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti–COVID-19 drug design

Wioletta Rut, Zongyang Lv, Mikołaj Żmudziński et al. · Science Advances · 2020 · 483 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +14

Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia

Digant Nayak, Yingqian Huo, Timothy Weixin Kwang et al. · Neuroscience · 2009 · 150 citations

Life Sciences, Neurobiology, Neuroscience +16

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity,

Dongwen Lv, Pratik Pal, Xingui Liu et al. · Nature Communications · 2021 · 148 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +12

Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL

Digant Nayak, Dongwen Lv, Yaxia Yuan et al. · Nature Communications · 2024 · 47 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase

Mikołaj Żmudziński, Wioletta Rut, Kamila Olech et al. · Scientific Reports · 2023 · 43 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

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