Concepedia

Yaxia Yuan

YY

39

Publications

2.6K

Citations

22

H-Index

2006

Active since

Affiliations

University of Kentucky(Current)

University of Florida

The University of Texas Health Science Center at San Antonio

Peking University

University of South Carolina Sumter

Yaxia Yuan is an author at University of Kentucky specializing in medicine, pharmacology, and drug discovery.

Top concepts

MedicinePharmacologyDrug DiscoveryBiochemistryNatural SciencesMedicinal ChemistryCell BiologyCancer ResearchMolecular BiologyMolecular Docking

Publications per year

2006–2025

39

Publications

39

A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity

Sajid Khan, Xuan Zhang, Dongwen Lv et al. · Nature Medicine · 2019 · 608 citations · Full text

Oncology, Medicine, Potent Antitumor Activity +7

Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity

Yonghan He, Xuan Zhang, Jianhui Chang et al. · Nature Communications · 2020 · 246 citations · Full text

LigBuilder 2: A Practical <i>de Novo</i> Drug Design Approach

Yaxia Yuan, Jianfeng Pei, Luhua Lai · Journal of Chemical Information and Modeling · 2011 · 193 citations

Drug Target, Privileged Fragments, Medicinal Chemistry +18

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity,

Dongwen Lv, Pratik Pal, Xingui Liu et al. · Nature Communications · 2021 · 140 citations · Full text

Isatin Compounds as Noncovalent SARS Coronavirus 3C-like Protease Inhibitors

Lu Zhou, Ying Liu, Weilin Zhang et al. · Journal of Medicinal Chemistry · 2006 · 134 citations · Full text

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