Xuan Zhang

A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity

Sajid Khan, Xuan Zhang, Dongwen Lv et al. · Nature Medicine · 2019 · 608 citations · Full text

Oncology, Medicine, Potent Antitumor Activity +7

Discovery of piperlongumine as a potential novel lead for the development of senolytic agents

Yingying Wang, Jianhui Chang, Xingui Liu et al. · Aging · 2016 · 262 citations · Full text

Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity

Yonghan He, Xuan Zhang, Jianhui Chang et al. · Nature Communications · 2020 · 246 citations · Full text

A Biodegradable Low Molecular Weight Polyethylenimine Derivative as Low Toxicity and Efficient Gene Vector

Yuting Wen, Shirong Pan, Xin Luo et al. · Bioconjugate Chemistry · 2009 · 166 citations

Low Toxicity, Engineering, Bioplastic +18

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity,

Dongwen Lv, Pratik Pal, Xingui Liu et al. · Nature Communications · 2021 · 140 citations · Full text