Mireille Gaudreault

High-Throughput Cytochrome P450 Inhibition Assays Using Laser Diode Thermal Desorption-Atmospheric Pressure Chemical Ionization-Tandem Mass Spectrometry

Jin Wu, Christopher S. Hughes, Pierre Picard et al. · Analytical Chemistry · 2007 · 107 citations

Medicine, Pharmacology, Toxicology +17

The Discovery of 4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic Acid (MK-2894), A Potent and Selective Prostaglandin E₂Subtype 4 Receptor Antagonist

Marc Blouin, Yongxin Han, Jason D. Burch et al. · Journal of Medicinal Chemistry · 2010 · 34 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Discovery, biosynthesis, and structure elucidation of new metabolites of norandrostenedione using in vitro systems

Jean-François Lévesque, Mireille Gaudreault, Yves Aubin et al. · Steroids · 2005 · 20 citations

Life Sciences, Biochemistry, Pharmacology +11

Design and optimization of a substituted amino propanamide series of renin inhibitors for the treatment of hypertension

Austin Chen, Christopher I. Bayly, Olivier Bezençon et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 17 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Addressing time-dependent CYP 3A4 inhibition observed in a novel series of substituted amino propanamide renin inhibitors, a case study

Austin Chen, Daniel Dubé, Laurence Dubé et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 16 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +7