Laurence Dubé

Discovery of MK-0952, a selective PDE4 inhibitor for the treatment of long-term memory loss and mild cognitive impairment

Michel Gallant, Renée Aspiotis, Stephen H. Day et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 44 citations · Full text

Medicine, Neuroscience, Pharmacology +11

Discovery of Two Novel Antiplatelet Clinical Candidates (BMS-986120 and BMS-986141) That Antagonize Protease-Activated Receptor 4

E. Scott Priestley, Jacques Banville, Daniel H. Deon et al. · Journal of Medicinal Chemistry · 2022 · 27 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +14

Design and optimization of a substituted amino propanamide series of renin inhibitors for the treatment of hypertension

Austin Chen, Christopher I. Bayly, Olivier Bezençon et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 17 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Addressing time-dependent CYP 3A4 inhibition observed in a novel series of substituted amino propanamide renin inhibitors, a case study

Austin Chen, Daniel Dubé, Laurence Dubé et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 16 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +7

New approach toward the total synthesis of (+)-aphidicolin by tandem transannular Diels–Alder/aldol strategy

François Bilodeau, Laurence Dubé, Pierre Deslongchamps · Tetrahedron · 2003 · 16 citations

Pharmacy, Medicinal Chemistry, Synthetic Medicinal Chemistry +3