Jean-François Lévesque

High-Throughput Cytochrome P450 Inhibition Assays Using Laser Diode Thermal Desorption-Atmospheric Pressure Chemical Ionization-Tandem Mass Spectrometry

Jin Wu, Christopher S. Hughes, Pierre Picard et al. · Analytical Chemistry · 2007 · 107 citations

Medicine, Pharmacology, Toxicology +17

The identification of 4,7-disubstituted naphthoic acid derivatives as UDP-competitive antagonists of P2Y14

Jacques Yves Gauthier, Michel Belley, Denis Deschênes et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 57 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +5

Applying the pro-drug approach to afford highly bioavailable antagonists of P2Y14

Joël Robichaud, Jean‐François Fournier, Sébastien Gagné et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 50 citations

Pharmacy, Medicinal Chemistry, Pharmacology +4

Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases

Michel Gallant, Christian Beaulieu, Carl Berthelette et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 49 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Discovery of MK-0952, a selective PDE4 inhibitor for the treatment of long-term memory loss and mild cognitive impairment

Michel Gallant, Renée Aspiotis, Stephen H. Day et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 44 citations · Full text

Medicine, Neuroscience, Pharmacology +11