Hassan Afify

Galangin mitigates DOX-induced cognitive impairment in rats: Implication of NOX-1/Nrf-2/HMGB1/TLR4 and TNF-α/MAPKs/RIPK/MLKL/BDNF

Sarah A. Abd El‐Aal, Mohamed Abdelrahman, Ahmed Reda et al. · NeuroToxicology · 2022 · 35 citations

Neurodegenerative Diseases, Medicine, Neuroprotection +3

The modulatory effects of cinnamaldehyde on uric acid level and IL-6/JAK1/STAT3 signaling as a promising therapeutic strategy against benign prostatic hyperplasia

Hassan Afify, Amira M. Abo‐Youssef, Hanaa M. Abdel-Rahman et al. · Toxicology and Applied Pharmacology · 2020 · 25 citations

Inflammation, Urology, Medicine +7

Febuxostat attenuates testosterone-induced benign prostatic hyperplasia in rats via inhibiting JAK/STAT axis

Amira M. Abo‐Youssef, Hassan Afify, Amany A. Azouz et al. · Life Sciences · 2020 · 24 citations

Urology, Signal Transduction, Endocrine Mechanism +10

Fragment merging approach for the design of thiazole/thiazolidine clubbed pyrazoline derivatives as anti-inflammatory agents: Synthesis, biopharmacological evaluation and molecular modeling studies

Mohamed K. Elgohary, Soha R. Abd El Hadi, Mahmoud F. Abo-Ashour et al. · Bioorganic Chemistry · 2023 · 22 citations

Combinatorial Chemistry, Medicinal Chemistry, Biopharmacological Evaluation +12

Cyclooxygenase-2 activates EGFR–ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia

Mohammed E. Abo‐El Fetoh, Maha M. Abdel‐Fattah, Wafaa R. Mohamed et al. · Inflammopharmacology · 2022 · 20 citations · Full text