Mohamed K. Elgohary

Novel imidazo[2,1-b]thiazoles and imidazo[1,2-a]pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological evaluations

Mahmoud S Elkotamy, Mohamed K. Elgohary, Sara T. Al‐Rashood et al. · Bioorganic Chemistry · 2024 · 37 citations

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +11

Fragment merging approach for the design of thiazole/thiazolidine clubbed pyrazoline derivatives as anti-inflammatory agents: Synthesis, biopharmacological evaluation and molecular modeling studies

Mohamed K. Elgohary, Soha R. Abd El Hadi, Mahmoud F. Abo-Ashour et al. · Bioorganic Chemistry · 2023 · 22 citations

Combinatorial Chemistry, Medicinal Chemistry, Biopharmacological Evaluation +12

Design, synthesis, and evaluation of novel benzofuran and pyrazole-based derivatives as dual AChE/BuChE inhibitors with antioxidant properties for Alzheimer's disease management

Mahmoud S Elkotamy, Mohamed K. Elgohary, Mahmoud Abdelrahman Alkabbani et al. · European Journal of Medicinal Chemistry · 2024 · 17 citations

Pyrazole-based Derivatives, Medicinal Chemistry, Alzheimer's Disease +10

Design, Synthesis and Biological Assessment of N′-(2-Oxoindolin-3-ylidene)-6-methylimidazo[2,1-b]thiazole-5-carbohydrazides as Potential Anti-Proliferative Agents toward MCF-7 Breast Cancer

Najla A. Alshaye, Mohamed K. Elgohary, Mahmoud S Elkotamy et al. · Pharmaceuticals · 2024 · 15 citations · Full text

Fenamates and ibuprofen as foundational components in the synthesis of innovative, targeted COX-2 anti-inflammatory drugs, undergoing thorough biopharmacological assessments and in-silico computational studies

Mohamed K. Elgohary, Mahmoud S Elkotamy, Mahmoud Abdelrahman Alkabbani et al. · Bioorganic Chemistry · 2024 · 15 citations