Ralph R. Alcendor

Sirt1 Regulates Aging and Resistance to Oxidative Stress in the Heart

Ralph R. Alcendor, Shumin Gao, Peiyong Zhai et al. · Circulation Research · 2007 · 1.1K citations

Lifespan Extension, Reductive Stress, Systems Biology +15

Silent Information Regulator 2α, a Longevity Factor and Class III Histone Deacetylase, Is an Essential Endogenous Apoptosis Inhibitor in Cardiac Myocytes

Ralph R. Alcendor, Lorrie A. Kirshenbaum, Shin‐ichiro Imai et al. · Circulation Research · 2004 · 301 citations

Heart Failure, Apoptosis, Cell Death +20

PPARα-Sirt1 Complex Mediates Cardiac Hypertrophy and Failure through Suppression of the ERR Transcriptional Pathway

Shinichi Oka, Ralph R. Alcendor, Peiyong Zhai et al. · Cell Metabolism · 2011 · 197 citations · Full text

Cardiac Muscle, Transcriptional Regulation, Heart Failure +9

Histone H2A.z Is Essential for Cardiac Myocyte Hypertrophy but Opposed by Silent Information Regulator 2α

Ieng-Yi Chen, Jacqueline Lypowy, Jayashree Pain et al. · Journal of Biological Chemistry · 2006 · 98 citations · Full text

Histone Modifications, Cardiac Muscle, Epigenetic Change +27

Autophagy Plays an Essential Role in Mediating Regression of Hypertrophy during Unloading of the Heart

Nirmala Hariharan, Yoshiyuki Ikeda, Chull Hong et al. · PLoS ONE · 2013 · 93 citations · Full text