Xavier Jacq

Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor

Xavier Jacq, Christel Brou, Yves Lutz et al. · Cell · 1994 · 402 citations

Life Sciences, Biochemistry, Molecular Biology +17

Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells

Frédéric Colland, Étienne Formstecher, Xavier Jacq et al. · Molecular Cancer Therapeutics · 2009 · 320 citations · Full text

Medicine, Cancer Biology, Oncology +13

Functional Proteomics Mapping of a Human Signaling Pathway

Frédéric Colland, Xavier Jacq, Virginie Trouplin et al. · Genome Research · 2004 · 316 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Function of TAFII-containing complex without TBP in transcription by RNA polymerase II

Elżbieta Wieczorek, Marjorie Brand, Xavier Jacq et al. · Nature · 1998 · 249 citations

Life Sciences, Genetics, Molecular Biology +13

Discovery of 4-{4-[(3<i>R</i>)-3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1<i>H</i>-indole (AZ20): A Potent and Selective Inhibitor of ATR Protein Kinase with Monotherapy in Vivo Antitumor Activity

Kevin M. Foote, Kevin Blades, Anna Cronin et al. · Journal of Medicinal Chemistry · 2013 · 215 citations · Full text

Medicine, Oncology, Pharmacology +13