Liya Kang

Discovery of Tyrosine-Based Potent and Selective Melanocortin-1 Receptor Small-Molecule Agonists with Anti-inflammatory Properties

Timothy F. Herpin, Guixue Yu, Kenneth E. Carlson et al. · Journal of Medicinal Chemistry · 2003 · 66 citations · Full text

Immunology, Dermatology, Skin Pigmentation +16

A selective small molecule agonist of the melanocortin-1 receptor inhibits lipopolysaccharide-induced cytokine accumulation and leukocyte infiltration in mice

Liya Kang, Kim W. McIntyre, Kathleen M. Gillooly et al. · Journal of Leukocyte Biology · 2006 · 41 citations

Lung Inflammation, Immunology, Immune Regulation +16

Discovery of pyrazine carboxamide CB1 antagonists: The introduction of a hydroxyl group improves the pharmaceutical properties and in vivo efficacy of the series

Bruce A. Ellsworth, Ying Wang, Yeheng Zhu et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 36 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Hydroxyl Group +12

Growth differentiation factor 15 neutralization does not impact anorexia or survival in lipopolysaccharide-induced inflammation

Danna M. Breen, Srinath Jagarlapudi, Anita Patel et al. · iScience · 2021 · 25 citations · Full text

Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation

Ella Fung, Liya Kang, Diana Sapashnik et al. · Scientific Reports · 2021 · 19 citations · Full text