Paola Dessanti

Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent

Paola Vianello, Oronza A. Botrugno, Anna Cappa et al. · Journal of Medicinal Chemistry · 2015 · 82 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Thieno[3,2-<i>b</i>]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration

Luca Sartori, Ciro Mercurio, Federica Amigoni et al. · Journal of Medicinal Chemistry · 2017 · 74 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Thieno[3,2-<i>b</i>]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure–Activity Relationship

Paola Vianello, Luca Sartori, Federica Amigoni et al. · Journal of Medicinal Chemistry · 2017 · 71 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: A novel class of irreversible inhibitors of histone demethylase KDM1A

Paola Vianello, Oronza A. Botrugno, Anna Cappa et al. · European Journal of Medicinal Chemistry · 2014 · 56 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Comprehensive <i>in Vitro</i> Characterization of the LSD1 Small Molecule Inhibitor Class in Oncology

Natalia Sacilotto, Paola Dessanti, Michele MP Lufino et al. · ACS Pharmacology & Translational Science · 2021 · 42 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15