Ciro Mercurio

Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer

Raffaella Di Micco, Gabriele Sulli, Miryana Dobreva et al. · Nature Cell Biology · 2011 · 369 citations

Medicine, Cancer Biology, Molecular Biology +12

Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis

Marta Molinari, Ciro Mercurio, Jorge Dominguez et al. · EMBO Reports · 2000 · 199 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Identification of <i>N</i>,1,4,4-Tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1<i>H</i>-pyrazolo[4,3-<i>h</i>]quinazoline-3-carboxamide (PHA-848125), a Potent, Orally Available Cyclin Dependent Kinase Inhibitor

Maria Gabriella Brasca, Nadia Amboldi, Dario Ballinari et al. · Journal of Medicinal Chemistry · 2009 · 128 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Toward Highly Potent Cancer Agents by Modulating the C-2 Group of the Arylthioindole Class of Tubulin Polymerization Inhibitors

Giuseppe La Regina, Ruoli Bai, Whilelmina Maria Rensen et al. · Journal of Medicinal Chemistry · 2012 · 124 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Cyclin-Dependent Kinase 2 Functions in Normal DNA Repair and Is a Therapeutic Target in BRCA1-Deficient Cancers

Andrew J. Deans, Kum Kum Khanna, Carolyn J. McNees et al. · Cancer Research · 2006 · 121 citations

Life Sciences, Cancer Biology, Oncology +17