Elizabeth A. Eckman

Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain <i>in vivo</i>

Wesley Farris, Stefan Mansourian, Yang Chang et al. · Proceedings of the National Academy of Sciences · 2003 · 1.5K citations · Full text

Degradation of the Alzheimer's Amyloid β Peptide by Endothelin-converting Enzyme

Elizabeth A. Eckman, Dana Kim Reed, Christopher B. Eckman · Journal of Biological Chemistry · 2001 · 335 citations · Full text

Amyloid-β peptide levels in brain are inversely correlated with insulysin activity levels <i>in vivo</i>

Bonnie C. Miller, Elizabeth A. Eckman, Kumar Sambamurti et al. · Proceedings of the National Academy of Sciences · 2003 · 293 citations

Partial Loss-of-Function Mutations in Insulin-Degrading Enzyme that Induce Diabetes also Impair Degradation of Amyloid β-Protein

Wesley Farris, Stefan Mansourian, Malcolm A. Leissring et al. · American Journal Of Pathology · 2004 · 260 citations · Full text

Induce Diabetes, Biochemistry, Protein Folding +10

Cellular prion protein regulates β-secretase cleavage of the Alzheimer's amyloid precursor protein

Edward T. Parkin, Nicole T. Watt, Ishrut Hussain et al. · Proceedings of the National Academy of Sciences · 2007 · 259 citations · Full text

Creutzfeldt-jakob Disease, β-Secretase Cleavage, Proteasome +18