Elizabeth A. Eckman

Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain <i>in vivo</i>

Wesley Farris, Stefan Mansourian, Yang Chang et al. · Proceedings of the National Academy of Sciences · 2003 · 1.5K citations · Full text

Life Sciences, Genetics, Neuroscience +15

Degradation of the Alzheimer's Amyloid β Peptide by Endothelin-converting Enzyme

Elizabeth A. Eckman, Christopher B. Eckman · Journal of Biological Chemistry · 2001 · 336 citations · Full text

Life Sciences, Biochemistry, Neuroscience +10

Amyloid-β peptide levels in brain are inversely correlated with insulysin activity levels <i>in vivo</i>

Bonnie C. Miller, Elizabeth A. Eckman, Kumar Sambamurti et al. · Proceedings of the National Academy of Sciences · 2003 · 294 citations

Life Sciences, Neurobiology, Neuroscience +14

Partial Loss-of-Function Mutations in Insulin-Degrading Enzyme that Induce Diabetes also Impair Degradation of Amyloid β-Protein

Wesley Farris, Stefan Mansourian, Malcolm A. Leissring et al. · American Journal Of Pathology · 2004 · 264 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Alzheimer's Disease β-Amyloid Peptide Is Increased in Mice Deficient in Endothelin-converting Enzyme

Elizabeth A. Eckman, Christopher B. Eckman · Journal of Biological Chemistry · 2003 · 261 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16