David J. Rawson

Discovery of Clinical Candidate 4-[2-(5-Amino-1<i>H</i>-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-<i>N</i>-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of Na_V1.7

Nigel A. Swain, D. V. Batchelor, Serge Beaudoin et al. · Journal of Medicinal Chemistry · 2017 · 83 citations · Full text

Pharmacy, Clinical Pharmacokinetics, Pharmacology +17

Chiral oxazoline route to enantiomerically pure biphenyls: magnesio and copper mediated asymmetric hetero- and homo-coupling reactions

A. I. MEYERS, Todd D. Nelson, Henk E. Moorlag et al. · Tetrahedron · 2004 · 76 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11

A highly stereoselective synthesis of axially chiral biaryls. Application to the synthesis of a potential chiral catalysts.

A. I. MEYERS, Anton Meier, David J. Rawson · Tetrahedron Letters · 1992 · 62 citations

Natural Sciences, Chemistry, Catalysis +10

Asymmetric tandem additions to chiral naphthyloxazolines. A new and potent chiral auxiliary resulting in a major improvement in convenience and efficiency

David J. Rawson, A. I. MEYERS · The Journal of Organic Chemistry · 1991 · 57 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6

Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel

Thomas Ryckmans, Aisah A. Aubdool, Jennifer V. Bodkin et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 46 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15