Thomas Ryckmans

Rapid assessment of a novel series of selective CB2 agonists using parallel synthesis protocols: A Lipophilic Efficiency (LipE) analysis

Thomas Ryckmans, Martin P. Edwards, Val A. Horne et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 267 citations · Full text

Parallel Synthesis Protocols, Biochemistry, Functional Selectivity +8

Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of <i>Pseudomonas aeruginosa</i>

Roman Sommer, Stefanie Wagner, Katharina Rox et al. · Journal of the American Chemical Society · 2017 · 177 citations · Full text

Glycobiology, Drug Resistance, Medicinal Chemistry +17

The Discovery of a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain

S. Skerratt, Mark D. Andrews, Sharan K. Bagal et al. · Journal of Medicinal Chemistry · 2016 · 80 citations · Full text

Pain Therapy, Drug Target, Pan-trk Inhibitor +21

Anti-biofilm Agents against <i>Pseudomonas aeruginosa</i>: A Structure–Activity Relationship Study of <i>C</i>-Glycosidic LecB Inhibitors

Roman Sommer, Katharina Rox, Stefanie Wagner et al. · Journal of Medicinal Chemistry · 2019 · 70 citations · Full text

First dual NK1 antagonists–serotonin reuptake inhibitors: synthesis and SAR of a new class of potential antidepressants

Thomas Ryckmans, Laurent Balançon, Olivier Berton et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 69 citations · Full text

Functional Selectivity, Medicine, Psychotropic Medication +6