Loïc Laplanche

An Inter-laboratory Study to Evaluate the Effects of Medium Composition on the Differentiation and Barrier Function of Caco-2 Cell Lines

Flavia Zucco, Anne-Françoise Batto, Giovanna Bises et al. · Alternatives to Laboratory Animals · 2005 · 126 citations

Life Sciences, Cell Biology, Pharmacology +17

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

Alison Margolskee, Adam S. Darwich, Xavier Pépin et al. · European Journal of Pharmaceutical Sciences · 2016 · 67 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

IMI – oral biopharmaceutics tools project – evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds

Alison Margolskee, Adam S. Darwich, Xavier Pépin et al. · European Journal of Pharmaceutical Sciences · 2016 · 43 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +10

Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins

Laurent Salphati, Xiaoyan Chu, Liangfu Chen et al. · Drug Metabolism and Disposition · 2014 · 40 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Genomic Knockout of Endogenous Canine P-Glycoprotein in Wild-Type, Human P-Glycoprotein and Human BCRP Transfected MDCKII Cell Lines by Zinc Finger Nucleases

Dominik Gartzke, Jürgen Delzer, Loïc Laplanche et al. · Pharmaceutical Research · 2014 · 31 citations

Life Sciences, Molecular Biology, Molecular Genetics +7