Jason S. Ngui

Cytochrome P450 3A4-Mediated Bioactivation of Raloxifene:  Irreversible Enzyme Inhibition and Thiol Adduct Formation

Qing Chen, Jason S. Ngui, George A. Doss et al. · Chemical Research in Toxicology · 2002 · 156 citations

Gynecology, Pharmacotherapy, Experimental Pharmacology +20

In vitro stimulation of warfarin metabolism by quinidine: increases in the formation of 4'- and 10-hydroxywarfarin.

Jason S. Ngui, Qing Chen, Magang Shou et al. · PubMed · 2001 · 98 citations

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +14

Bioactivation of diclofenac via benzoquinone imine intermediates-identification of urinary mercapturic acid derivatives in rats and humans.

Grace K. Poon, Qing Chen, Yohannes Teffera et al. · PubMed · 2001 · 90 citations

Pharmaceutical Science, Benzoquinone Imine Intermediates, Pharmacotherapy +18

Cytochrome P450 3A4-Mediated Interaction of Diclofenac and Quinidine

Jason S. Ngui, Wei Tang, Ralph A. Stearns et al. · Drug Metabolism and Disposition · 2000 · 73 citations

In Vitro Bioactivation of Dihydrobenzoxathiin Selective Estrogen Receptor Modulators by Cytochrome P450 3A4 in Human Liver Microsomes:  Formation of Reactive Iminium and Quinone Type Metabolites

Zhoupeng Zhang, Qing Chen, Ying Li et al. · Chemical Research in Toxicology · 2005 · 59 citations

Gynecology, Bis-cyano Adduct, Toxicological Mechanism +21