Yohannes Teffera

Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase

Brian K. Albrecht, Jean-Christophe Harmange, David Bauer et al. · Journal of Medicinal Chemistry · 2008 · 138 citations · Full text

Combinatorial Chemistry, Chemoprevention Strategy, Selective Inhibitors +22

Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators

Xin Huang, P.L. Shaffer, Shawn Ayube et al. · Nature Structural & Molecular Biology · 2016 · 122 citations

Molecular Pharmacology, Biochemistry, G Protein-coupled Receptor +9

Localization and Quantification of Drugs in Animal Tissues by Use of Desorption Electrospray Ionization Mass Spectrometry Imaging

Ramin Vismeh, Daniel J. Waldon, Yohannes Teffera et al. · Analytical Chemistry · 2012 · 106 citations

Engineering, Biological Mass Spectrometry, Animal Tissues +26

Substituted piperazines as novel dipeptidyl peptidase IV inhibitors

Linda Brockunier, Jiafang He, Lawrence F. Colwell et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 97 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +6

Discovery of a Potent, Selective, and Orally Bioavailable c-Met Inhibitor: 1-(2-Hydroxy-2-methylpropyl)-<i>N</i>-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1<i>H</i>-pyrazole-4-carboxamide (AMG 458)

Longbin Liu, Aaron Siegmund, Ning Xi et al. · Journal of Medicinal Chemistry · 2008 · 94 citations · Full text

Pharmaceutical Science, Metabolic Hot Spot, Chemoprevention Strategy +21