Rebecca J. Gum

Novel Homologues of CSBP/p38 MAP Kinase: Activation, Substrate Specificity and Sensitivity to Inhibition by Pyridinyl Imidazoles

Sanjay Kumar, Peter McDonnell, Rebecca J. Gum et al. · Biochemical and Biophysical Research Communications · 1997 · 499 citations

Signal Transduction, Signaling Pathway, Biochemistry +11

PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice

Bradley A. Zinker, Cristina M. Rondinone, James M. Trevillyan et al. · Proceedings of the National Academy of Sciences · 2002 · 412 citations · Full text

Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites Including Closely Spaced PEA3/ets and AP-1 Sequences

Rebecca J. Gum, Ernst Lengyel, Jose Juarez et al. · Journal of Biological Chemistry · 1996 · 347 citations · Full text

Regulation of 92 kDa type IV collagenase expression by the jun aminoterminal kinase- and the extracellular signal-regulated kinase-dependent signaling cascades

Rebecca J. Gum, H Wang, Ernst Lengyel et al. · Oncogene · 1997 · 235 citations

Cell Physiology, Systems Biology, Signal Transduction +12

Acquisition of Sensitivity of Stress-activated Protein Kinases to the p38 Inhibitor, SB 203580, by Alteration of One or More Amino Acids within the ATP Binding Pocket

Rebecca J. Gum, Megan M. McLaughlin, Sanjay Kumar et al. · Journal of Biological Chemistry · 1998 · 226 citations · Full text