HER2-Mediated Internalization of Cytotoxic Agents in <i>ERBB2</i> Amplified or Mutant Lung Cancers

Bob T. Li, Flavia Michelini, Sandra Misale, +45

Cancer Discovery

Antagonism of EGFR and HER3 Enhances the Response to Inhibitors of the PI3K-Akt Pathway in Triple-Negative Breast Cancer

Jessica J. Tao, Pau Castel, Nina Radosevic‐Robin, +23

Science Signaling

Breast OncologyOncologySignaling PathwayMedicineReceptor Tyrosine Kinase +13

ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation

James Monypenny, Hanna Milewicz, Fabian Flores‐Borja, +22

Cell Reports

ImmunologyExtracellular MicrovesiclesPd-l1 PresentationImmunotherapyCancer Biology +17

Proapoptotic Kinase MST2 Coordinates Signaling Crosstalk between RASSF1A, Raf-1, and Akt

David Romano, David Matallanas, Gregory Weitsman, +3

Cancer Research

Cancer ResearchSignal TransductionMitogenic StimulationSignaling PathwayCell Regulation +13

Estrogen Receptor-α Phosphorylated at Ser118 Is Present at the Promoters of Estrogen-Regulated Genes and Is Not Altered Due to HER-2 Overexpression

Gregory Weitsman, Lin Li, G. Skliris, +7

Cancer Research

Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface

Jeroen Claus, Gargi Patel, Flavia Autore, +16

eLife

Ado-trastuzumab emtansine in patients with <i>HER2</i> amplified salivary gland cancers (SGCs): Results from a phase II basket trial.

Bob T. Li, Ronglai Shen, Michael Offin, +17

Journal of Clinical Oncology

MedicineMetronomic TherapyImmunologyHer2 AmplificationPathology +11

Assessment of multiple different estrogen receptor-β antibodies for their ability to immunoprecipitate under chromatin immunoprecipitation conditions

Gregory Weitsman, G. Skliris, Kanyarat Ung, +4

Breast Cancer Research and Treatment

Chromatin Immunoprecipitation ConditionsHormonal ReceptorImmunologyGynecologyEndocrinology +3

From autoinhibition to inhibition in trans: the Raf-1 regulatory domain inhibits Rok-α kinase activity

Théodora Niault, Izabela Sobczak, Katrin Meissl, +11

The Journal of Cell Biology

Effect of Phosphorylation on EGFR Dimer Stability Probed by Single-Molecule Dynamics and FRET/FLIM

Oana Coban, Laura C. Zanetti-Dominguez, Daniel R. Matthews, +14

Biophysical Journal