Xavier Carette

Synthetic EthR inhibitors boost antituberculous activity of ethionamide

Nicolas Willand, Bertrand Dirié, Xavier Carette et al. · Nature Medicine · 2009 · 171 citations

Synthetic Ethr Inhibitors, Medicine, Pharmacotherapy +5

Investigating essential gene function in<i>Mycobacterium tuberculosis</i>using an efficient CRISPR interference system

Atul K. Singh, Xavier Carette, Lakshmi‐Prasad Potluri et al. · Nucleic Acids Research · 2016 · 164 citations · Full text

Engineering, Molecular Biology, Molecular Genetics +17

Ethionamide Boosters: Synthesis, Biological Activity, and Structure−Activity Relationships of a Series of 1,2,4-Oxadiazole EthR Inhibitors

Marion Flipo, Matthieu Desroses, Nathalie Lecat‐Guillet et al. · Journal of Medicinal Chemistry · 2011 · 84 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +17

Multisystem Analysis of <i>Mycobacterium tuberculosis</i> Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface

Xavier Carette, John Platig, David C. Young et al. · mBio · 2018 · 66 citations · Full text

Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands

Xavier Carette, Nicolas Blondiaux, Eve Willery et al. · Nucleic Acids Research · 2011 · 34 citations · Full text

Molecular Biology, Chemical Biology, Protein Synthesis +21