Nathalie Lecat‐Guillet

Mechanism of competence activation by the <scp>ComRS</scp> signalling system in streptococci

Laetitia Fontaine, Philippe Goffin, Hélène Dubout et al. · Molecular Microbiology · 2013 · 97 citations

Microbial Pathogens, Bacteriology, Molecular Biology +16

Ethionamide Boosters: Synthesis, Biological Activity, and Structure−Activity Relationships of a Series of 1,2,4-Oxadiazole EthR Inhibitors

Marion Flipo, Matthieu Desroses, Nathalie Lecat‐Guillet et al. · Journal of Medicinal Chemistry · 2011 · 84 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +17

Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors

Marion Flipo, Matthieu Desroses, Nathalie Lecat‐Guillet et al. · Journal of Medicinal Chemistry · 2011 · 70 citations · Full text

Discovery of Novel <i>N</i>-Phenylphenoxyacetamide Derivatives as EthR Inhibitors and Ethionamide Boosters by Combining High-Throughput Screening and Synthesis

Marion Flipo, Nicolas Willand, Nathalie Lecat‐Guillet et al. · Journal of Medicinal Chemistry · 2012 · 48 citations · Full text

Bioorganic Chemistry, Drug Resistance, Medicinal Chemistry +18

Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands

Xavier Carette, Nicolas Blondiaux, Eve Willery et al. · Nucleic Acids Research · 2011 · 34 citations · Full text

Molecular Biology, Chemical Biology, Protein Synthesis +21