Akira Yukimasa

SmI₂-Mediated Reduction of γ,γ-Difluoro-α,β-enoates with Application to the Synthesis of Functionalized (<i>Z</i>)-Fluoroalkene-Type Dipeptide Isosteres

Akira Otaka, Junko Watanabe, Akira Yukimasa et al. · The Journal of Organic Chemistry · 2004 · 88 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

New access to α-substituted (Z)-fluoroalkene dipeptide isosteres utilizing organocopper reagents under ‘reduction–oxidative alkylation (R–OA)’ conditions

Akira Otaka, Hideaki Watanabe, Akira Yukimasa et al. · Tetrahedron Letters · 2001 · 46 citations

Natural Sciences, Chemistry, Medicinal Chemistry +12

Synthesis of (Z)-fluoroalkene dipeptide isosteres utilizing organocopper-mediated reduction of γ,γ-difluoro-α,β-enoates

Akira Otaka, Hideaki Watanabe, Etsuko Mitsuyama et al. · Tetrahedron Letters · 2001 · 42 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

Application of samarium diiodide (SmI₂)-induced reduction of γ-acetoxy-α,β-enoates with α-specific kinetic electrophilic trapping for the synthesis of amino acid derivatives

Akira Otaka, Akira Yukimasa, Junko Watanabe et al. · Chemical Communications · 2003 · 28 citations

Natural Sciences, Biochemistry, Chemistry +8

Hit to lead SAR study on benzoxazole derivatives for an NPY Y5 antagonist

Naoki Omori, Naoki Kouyama, Akira Yukimasa et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 16 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16