Naoki Kouyama

Design, synthesis and identification of novel benzimidazole derivatives as highly potent NPY Y5 receptor antagonists with attractive in vitro ADME profiles

Yuusuke Tamura, Naoki Omori, Naoki Kouyama et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 23 citations · Full text

Medicinal Chemistry, Drug Target, Novel Benzimidazole Derivatives +10

Hit to lead SAR study on benzoxazole derivatives for an NPY Y5 antagonist

Naoki Omori, Naoki Kouyama, Akira Yukimasa et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 16 citations · Full text

Npy Y5 Antagonist, Medicine, Sar Study +7

Identification of a novel and orally available benzimidazole derivative as an NPY Y5 receptor antagonist with in vivo efficacy

Yuusuke Tamura, Naoki Omori, Naoki Kouyama et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 15 citations · Full text

Biochemistry, Medicine, Available Benzimidazole Derivative +6

Identification of a novel benzimidazole derivative as a highly potent NPY Y5 receptor antagonist with an anti-obesity profile

Yuusuke Tamura, Kyouhei Hayashi, Naoki Omori et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 10 citations · Full text

Drug Target, Biochemistry, Functional Selectivity +8