Frank Kerrigan

4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2<i>H</i>-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1

Keith Menear, Claire Adcock, Robert Boulter et al. · Journal of Medicinal Chemistry · 2008 · 572 citations · Full text

Medicinal Chemistry, Polymerase Activation, Oral Bioavailability +15

Phthalazinones. Part 1: The design and synthesis of a novel series of potent inhibitors of poly(ADP-ribose)polymerase

Vincent M. Loh, Xiaoling Cockcroft, Krystyna J. Dillon et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 92 citations · Full text

Combinatorial Chemistry, Novel Series, Biochemistry +10

Phthalazinones 2: Optimisation and synthesis of novel potent inhibitors of poly(ADP-ribose)polymerase

Xiaoling Cockcroft, Krystyna J. Dillon, Lesley Dixon et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 87 citations · Full text

Biochemistry, Natural Sciences, Biocatalysis +10

<i>N</i>-Substituted (2,3-Dihydro-1,4-benzodioxin-2-yl)methylamine Derivatives as D₂ Antagonists/5-HT_1A Partial Agonists with Potential as Atypical Antipsychotic Agents

Alan M. Birch, Paul A. Bradley, J. C. GILL et al. · Journal of Medicinal Chemistry · 1999 · 46 citations · Full text

Psychotropic Medication, Psychopharmacology, Social Sciences +16

Synthesis of arylpiperazines via palladium-catalysed aromatic amination reactions of bromoarenes with N-tert-butoxycarbonylpiperazine

Frank Kerrigan, Claire Martin, Gerard H. Thomas · Tetrahedron Letters · 1998 · 40 citations

Engineering, Organic Chemistry, Catalysis +3